Medicine is the science that has great religious value and its importance has been emphasized. The Holy Quran in many verses has proposed the issue of body and soul sanitary and treatment. Some of the Quran verses have considered the issue of prevention and treatment of diseases of the human body, and other categories, have discussed the prevention, and treatment of mental illnesses. Using verses from the Holy Quran which have medically important role in physical and mental health in Muslims requires accurate understanding of the medical verses, Since the danger of misconception of verses which occasionally is done for the proving of scientific miracle of Quran verses, is equal to interpretation of vote and this can lead the Muslims to be skeptical to Quran Verses. Interpretation of the medical verses of Quran, sometimes, has been based on extracting all science of Quran due to the lack of a systematic and comprehensive method. This method which has been prevalent between scientists is inappropriate and wrong method. Another common method in interpretation of medical verses is imposition of findings in medical sciences or adopting them with Quran verses. This interpretation was also absurd and improper, because the Qur’an despite some references in the different field of science is not a pure science book to mention all of the science details. This is while Quran is a book of guidance for all the people in the world. Hence, the way to avoid major medical misconceptions in interpreting the verses of the Qur’an, is obtaining the correct method in interpretation of medical verses that is what has been addressed in this paper.