Wart is a circular, self-inoculation, and contagious appendage which in Iranian traditional medicine is called “suloul”, and has different types and causes. Wart has long-term period of treatment with symptoms of multiple relapses which involve larger surfaces. In classic medicine, wart is a viral infection and has no definite medical treatment. Objectives: The current study aimed to evaluate wart and its treatment from the viewpoint of Iranian traditional medicine. Materials and Methods: The current study was a combination of fieldwork and library research conducted according to the traditional medicine reference books. Results: Physicians of Iranian traditional medicine believe that the origin of wart is sauda (black bile) or a combination of them; and advise various, economic and low risk treatments. Conclusions: With the help of Iranian traditional medicine, and according to the six essential principles, the temperament of the patient should be modified, the temperament which caused the disease should be eliminated, and the return of disease should be prevented. Also, with the help of topical treatments, its scars should be removed.