The Sacred Art of Islam has undoubtedly been born with the calligraphy of the Holy Quran. Afterwards, it was completed and evolved with decorating of this magnificent manifest. This process has had great effects on all fields of Islamic Art. In this research, the writer has discussed about the procedure of scribing the Holy Quran in the life time of the Holy Prophet (p.b.u.h) as well as the time of Uthman’s caliphate. Mus’hef of Imam has also been pointed out. It has been confirmed that at the time of the Holy Prophet (p.b.u.h), the scribers wrote the Holy Quran in a special manner known as Mekky or Madani or Hejazi style. In this essay a few pages of the two remaining manuscripts of the Holy Quran scribed by this style, have been talked about. By analyzing the styles of scribing these two copies, it is pointed out that the words and letters have been arranged and collected in a beautiful order regarding the symmetrical, harmony and balance of the shapes and sizes.